One-Two (Double Blow) bioattack Hidden in AIDS Vaccine Program? UW Gates

[global_fiefdom]

Dec. 7, 2011
UW scientist gets major boost in search for HIV vaccine

By Melinda Young

School of Pharmacy

Dr. Shiu-Lok Hu, HIV vaccine researcher at the UW School of Pharmacy

Team Photogenic

Dr. Shiu-Lok Hu, HIV vaccine researcher at the UW School of Pharmacy

In 2009, when researchers from the RV144 trial in Thailand announced they had found the first indication of a possible vaccine protection against HIV, their discovery was based on an immunization regimen pioneered by a UW scientist more than two decades ago.

Dr. Shiu-Lok Hu, Gibaldi Endowed Professor of Pharmaceutics at the UW School of Pharmacy, created the “prime-boost” immunization method in the late 1980s while working at Oncogen. This method uses two vaccine components — a relatively harmless virus that delivers HIV proteins and primes the immune system, followed by booster shots of the HIV proteins themselves. This one-two punch approach activates both antibody and cell-mediated immune responses.

Now, as HIV/AIDS researchers worldwide seem to be moving closer to a possible HIV vaccine, Hu has received a vote of confidence from the Bill & Melinda Gates Foundation for his contributions to the field. The foundation awarded Hu a $6.7 million grant that will enable his research team to join the Consortium for AIDS Vaccine Discovery (CAVD), an international network of scientists launched by the Gates Foundation to design novel HIV vaccine candidates and advance the most promising candidates to clinical trials.

Hu’s research project is entitled, “Unmasking conserved epitopes on HIV envelope protein for vaccine design.” Two co-investigators on the project are from the Perelman School of Medicine at the University of Pennsylvania: Dr. Jim Hoxie, professor of medicine and director of the Penn Center for AIDS Research, and Dr. Drew Weissman, associate professor of medicine in the Division of Infectious Diseases. The third co-investigator is Dr. Shan Lu, professor of medicine, biochemistry and molecular pharmacology at the University of Massachusetts Medical School.

The goal of their four-year study is to build upon the success of the prime-boost strategy and to explore vaccine designs that may generate protective antibodies targeting the part of the virus it uses to bind to immune cells — the part widely considered the Achilles heel of the virus. Hu’s lab has previously shown that the removal of a specific glycan molecule on the envelope protein used by the virus to enter the host cell resulted in an enhanced ability of the mutant protein to induce neutralizing antibodies. Now Hu and his colleagues seek to uncover ways to further enhance this glycan-modified envelope vaccine design’s ability to provoke an immune response.

In other words, they hope to find a safe, effective vaccine that will help the immune system ward off HIV infection.

HIV infects more than 2 million people globally each year. Throughout the world, an estimated 33 million people are living with HIV/AIDS. While antiretroviral therapy can control progression to AIDS, it cannot cure or stop the spread of the disease.

“The successful development of safe and efficacious vaccines against these diseases represents our best hope for eradicating this pandemic in the long term,” said Hu. “The search for a vaccine is a humbling and daunting task as an individual scientist. But as a member of the CAVD and the AIDS research community, it is tremendously exciting and rewarding.”

Indeed, being part of the Consortium for AIDS Vaccine Discovery will allow Hu’s research team to tap into an international research network of more than 500 HIV/AIDS investigators across 94 institutions in 19 countries.

For his part, Hu has a highly active research program at the UW School of Pharmacy. He is currently part of three, multiyear, multi-institution National Institute of Allergy and Infectious Diseases HIV Vaccine Research and Design grants, for which his contributions total more than $9.5 million.

This new Gates Foundation grant, said Hu, will allow his team to leverage the expertise, resources and infrastructure of the top scientists in the field.

“We all know the challenges we face to develop a safe and effective vaccine against HIV/AIDS,” he said. “However, I believe we can make a difference if we commit ourselves and work together toward this worthwhile goal.”

The UW School of Pharmacy is the fifth ranked pharmacy school in the nation, according to U.S. News & World Report. Ranked No. 9 among pharmacy schools in National Institutes of Health grant funding, its faculty secured more than $15 million in overall research funding in fiscal year 2011. The School of Pharmacy educates professional pharmacists, develops scientific leaders and serves the community through health outreach and education.
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http://www.patientsville.com/vaccines/anth/blood-triglycerides-increased-anthrax-biothrax-2010.htm

Blood triglycerides increased from ANTHRAX (BIOTHRAX) 2010

Vaccine Manufacturer:EMERGENT BIOSOLU
Vaccine Code:ANTH
Vaccine Type:ANTHRAX VACCINE
Vaccine Name:ANTHRAX (BIOTHRAX)
Year Reported:2010
Symptom Reported:Blood triglycerides increased

ANTHRAX (BIOTHRAX) Side Effects Report #386666
ANTHRAX (BIOTHRAX) vaccine side effect was reported on 05/04/2010. Male patient, 41.0 years of age, was vaccinated with ANTHRAX (BIOTHRAX). Patient symptoms: Blood triglycerides increased, "Within 20 seconds post AVA vaccination he experienced severe burning to the AVA vaccine site as if ~hit by a bee~ that resolved to a sore arm (3-5/10) about 15 minutes later. However, bystanders noted his complexion went white. He sat down and was monitored for 15 min until complexion was normal. He denied any dizziness, nausea, visual changes, chest pain, difficulty breathing, or any paresthesia. Approximately one hour later driving home, he began to feel achy, sick with generalized joint and body aches, headache, and his throat was sore. He had ~swollen neck lymph nodes bilaterally~. That evening (<12 hours post vaccinations) he developed a fever 100.5 F with increased malaise, body aches, muscle weakness, and nausea (no vomiting). He slept fitfully awakening about midnight with difficulty breathing (inspiration), a sore throat, and the sensation of his throat closing. He reported his ~uvula was red and swollen~. He was evaluated 06 Oct 2008 am by his PCP Dr. who noted 2+ uvula swelling. Weight was 212 lbs and temperature 98.6 F. He was prescribed CLARITIN, BENADRYL, and MEDROL dose pack for presumed ~allergic reaction~. Follow up evaluation 3-4 hours later (06 Oct 2008) documented continued complaints of a sore throat (but better) without difficulty breathing, ~fever 100.5 F~, body-joint aches, severe muscle weakness, and axillary lymph node tenderness. His exam documented: temperature 98.1F, weight 213.2 lbs; a deviated septum; hyperemic; mildly edematous uvula, normal tongue with cobblestone appearing pharynx; AVA vaccine site mildly hyperemic with dressing to SPV site and normal hep B vaccine site; left axilla was mild-moderately tender to palpation without swelling/nodules; otherwise exam was normal. Neuro and musculoskeletal exams were intact with normal reflexes and without weakness. He was diagnosed with ~axillary lymphadenopathy and allergic reaction to anthrax vaccine~. No further AVA vaccine was recommended. Over the next week (Oct 6-12) he was unable to work. He complained of increasing weight gain" none"1986 recurrent aphthous ulcers to soft palate; 1998 high freg hearing loss right ear; 1994-2000 pneumonia x 4; 2001 chronic lower back pain and new onset headaches; 2002 hypercholesterolemia; 2002 dx hereditary spherocytosis; 2004/5 anxiety (on WELLBUTRIN, and MVA multiple injuries/fractures, ulnar nerve entrapment; 2006 hypertension (meds used in 2010); 2006 migraine headaches on""1. 12/22/09: CBC, SGPT, UA & CMP nl with chol 209, trig 296, HDL 38; TSH 5.692; 2. 1/19/10: CBC, renal function test (nl), ESR nl, SMA12, LFT, ANA neg, RF 9.5 (nl), CRP 0.7 (nl), Flo Cytometric analysis peripheral blood shows heterogeneous" . During the same period patient was treated with none pre vac; post vac Meds: TOPROL 25 mg daily; IMITREX prn; Lisinopril; SYNTHROID; TRAMADOL; Cyclobenzapine. Patient recovered.
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The double blow approach destroys the body's steroid balance and causes PTSD.
This vaccine is not safe. It is too much like the Anthrax vaccine that killed and maimed so many troops.
Don't do it. Please.

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http://www.rense.com/general67/vacc.htm  (sorry, rense)

Vaccines, Autism and
Gulf War Syndrome
From Dr. Betty Martini, D.Hum.
Bettym19@mindspring.com
8-15-5
 

This is an excellent report by Dr. Blaylock.
 
Dr. Blaylock is the author of: 'Excitotoxins: The Taste That Kills', 'Health & Nutrition Secrets To Save Your Life' and 'Cancer Strategies' all of which are shown on his site at
http://www.russellblaylockmd.com
 
An excitotoxin is a product that literally stimulates the neurons of the brain *to death causing permanent brain damage.* The two we think the most of are the aspartic acid in aspartame and MSG.
 
In Health & Nutrition Secrets, page 125, Dr. Blaylock says: "So, in the case of diet drinks in aluminum cans, the very toxic brain aluminum fluoride compound co-exists with multiple toxins found in aspartame, thus creating the most powerful government-approved toxic soup imaginable. With the strong association between aluminum, excitotoxins, aluminum fluoride complexes and Alzheimer's disease, it would be completely irresponsible to encourage people to consume this toxic mixture. Yet, this is done literally billions of times every year in advertising."
 
In the Gulf, these diet drinks sat on pallets as long as 8 weeks at a time, piled high, in 120 degree temperatures.
 
In the protest of the National Soft Drink Association at http://www.dorway.com, you will read that aspartame breaks down at 86 degrees. And it breaks down into a witches' brew of toxins including formaldehyde and diketopiperazine, a brain tumor agent that triggered brain tumors in original studies.
 
Aspartame destroys the immune system and central nervous system. It not only interacts with drugs because of damage to the mitochondria or life of the cell according to Dr. James Bowen, but as a chemical hypersensitization agent it interacts with vaccines and other toxins. In a lecture on www.dorway.com, Dr. Blaylock also says the reactions to aspartame are not allergic but *toxic*...
just like consuming arsenic and cyanide. Aspartame is an adjuvant and forms antigenic tissue, triggering immunologic attack. This is how it triggers lupus. The immune system turns against the victim's tissues.
 
In this article Dr. Blaylock brings out that it is accepted by most authorities that vaccines should not be given to individuals with impaired immunity for fear of triggering immune attacks on the central nervous system, such as encephalitis, nerve injuries (peripheral neuropathy, multiple sclerosis and allergic encephalomyelitis.
 
So, it's really a given with such a toxic soup the troops were exposed to, we truly are looking at diet drink catastrophe. This article makes it easy to understand Gulf War illness. A new study connects brain cancer in Gulf War vets to sarin, but researchers may not have known the aspartame laced pop they were drinking breaks down to a brain tumor agent. A USA Today article of July 26 states sarin has never been shown to cause cancer.
 
With all this information in mind, here is Dr. Blaylock's excellent article:
 
By Russell L. Blaylock
MD Neurosurgeon
 
Most have at least heard about the controversy surrounding possible harmful effects of some of the vaccines. What is less well known is that even greater dangers exist than are being conveyed to the general public. Much of this information is buried in highly technical scientific journals beyond the reach and understanding of the average person.
 
Of special concern is the relationship between vaccine policy, autism and the Gulf War Syndrome.
I shall use the Gulf War Syndrome as an example of a vaccine policy gone berserk, while including discussions of other dangers as well.
 
Most scientific observers have attributed the dramatic fall in infectious disease to the appearance of widespread vaccination, despite recent evidence that some of that credit is unjustified. For example, we know that improved public health measures and nutrition played a major role in the sudden decline in most of the infectious diseases plaguing mankind. Likewise, there is growing evidence that vaccinations are not providing the protection that they are touted to provide. For example, all cases of polio occurring after the introduction of the polio vaccine shave been traced to the vaccine itself. Similar findings have been shown for diphtheria.
 
Convinced that the victory over the major childhood infectious diseases was secondary to vaccine programs, public health officials began to add more diseases to the list, including haemophilus influenza type b, hepatitis B, measles, mumps and now even chickenpox. Present vaccination programs are exposing children to as many as 22 inoculations before attending school. More are being proposed. Driving much of this are the profits being made by vaccine manufacturers and a revolving door between medical university professors with financial interest in these companies and public health officials with the same interest.
 
Unfortunately, the science supporting the safety of unlimited vaccination of small children and adults does not exist. Most follow-up studies of vaccinated children last no more than two weeks after the vaccine is given, and many of the effects of vaccination on brain development are delayed much longer. In addition, most of these studies look only for blatantly obvious injuries and not subtle changes that can lead to serious future impairment.
 
There are a growing number of scientific studies that are demonstrating serious dangers in our present vaccine policy, including altered brain development, seizures and a loss of brain cell connections called synapses. These studies all point to over-vaccination as a real and present danger to our children, and in certain instances, to adults. Unfortunately, most pediatricians and family practitioners are completely unaware of these dangers. Most depend on their specialty societies, such as the American Academy of Pediatrics and the American Academy of Family Practice for answers concerning safety issues. Rarely do these physicians research these important topics themselves. For too often, those serving on vaccine boards within these specialty societies have a vested interest in the financial success of the companies involved, either as investments in stock or direct payments by the companies.
 
Much controversy and confusing data surrounds the cause of the Gulf War Syndrome (GWS), and despite numerous studies, little solid information as to the cause of the syndrome has appeared. Throughout the entire period since the first Gulf war the Pentagon has been reluctant to admit to a connection between this devastating syndrome (that has left tends of thousands of soldiers and their families chronically ill and many of these children deformed) and military policies on vaccination. Our soldiers were given approximately 17 vaccinations over a short period, despite manufacturer's warnings that many of the vaccines, were to be spaced over a year period. Several hypotheses have been proposed as to the cause of this syndrome, including neurotoxic and immunotoxic effects of pesticides, aspartame degradation products, chemical warfare agents released, toxins from spent uranium shells, combat stress and vaccines.
  
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"One-Two Swine Flu"

http://www.iraq-war.ru/article/205004

Three-Stage- “Swine Flu” Vaccinations-creates-perfect-cytokine-storm (Death)

The vaccine is to be given by a series of three injections. Speaking on the Republic Broadcasting Network with Dr. Rebecca Carley as host on July 11th, meta-analyst and vaccine researcher Patrick Jordan reported belief that the first injection will be for the purpose of turning off the victim’s immune system. The second injection will be for the purpose of loading people with deadly organisms. And the third injection will be to turn the immune system back on for the purpose of creating a cytokine storm that will deal a lethal blow to the body.

http://blogs.healthfreedomalliance.org/blog/2009/07/30/three-stage-vaccinations-may-create-perfect-cytokine-storm/


Squalene produces auto-immunity and eventually death in everyone who takes it”

vaccine4The vaccine is to be given by a series of three injections. Speaking on the Republic Broadcasting Network with Dr. Rebecca Carley as host on July 11th, meta-analyst and vaccine researcher Patrick Jordan reported belief that the first injection will be for the purpose of turning off the victim’s immune system. The second injection will be for the purpose of loading people with deadly organisms. And the third injection will be to turn the immune system back on for the purpose of creating a cytokine storm that will deal a lethal blow to the body.

In his chronicle of the connection between vaccines and death, Jordan pointed out that in 1915 the pertussis vaccine became available and was widely given. This bacterial poison from whopping cough, called pertussis coxon, so depresses the immune system that it is used in laboratories today to turn off nutrafils and reduce white blood cell counts. Then, in 1918, soldiers who had received the pertussis vaccine were deployed to Europe, where they were given another unknown vaccine. They were then exposed to a Lucite gas, which is an arsenic compound, and phosgenegas, a chlorine compound. As a result, their immune systems kicked in with a cytokine storm that killed many of the otherwise healthy young men. This is the 1,2,3 punch Jordan is warning will come again with the “swine flu” vaccinations.

We have been conditioned to think of external microbes as our enemy during a time of influenza. But our own immune systems are potentially more lethal. When the body detects foreign microorganisms indicating an infection, it can respond by overprotecting the site of that infection. In its hurry to get antibodies to the infection site, the body may dispatch so many that the level of cytokines becomes highly elevated, creating a cytokine storm that can be fatal. For example, during a lung infection, a cytokine storm can potentially block airways and result in suffocation. (What is a Cytokine Storm, www.wisegeek.com)

Jordan continued by painting a picture outlined in the WHO Memorandum Number 1 with a study that found virus infections make antibody and antigen complexes. These complexes can clog blood vessels or implant tissue, making the body eventually attack itself. The main focus of this study was kidney disease. Animals with induced immune system deficiency were infected with lethal virus until every single cell in their bodies reflected the disease. But for a time these animals ran around like there was nothing wrong with them because their immune system was so depressed that it was making no effort to fight the disease, and there was no immune response. The WHO experimenters then took their lab animals and stimulated the cell-mediated immune response, and the animals died immediately from their bodies attacking themselves in the kind of cytokine storm associated with the 1918 Spanish flu.

Even if this described scenario does not develop, Jordan points out that the current “swine flu” vaccine is made with an adjuvant that may contain a material poison, salmonella, or typhoid fever toxin, along with squalene. Although not known with certainty, the second round of injections given to the soldiers in 1918 is believed to have contained typhus. Squalene produces auto-immunity and eventually death in everyone who takes it.

Squalene contributed to the cascade reactions known as Gulf War Syndrome that left GIs with arthritis, fibromyalgia, lymphadenopathy, photosensitive rashes, chronic fatigue, chronic headaches, ulcers, dizziness, weakness, memory loss, seizures, mood changes, neuro-psychiatric problems, multiple sclerosis, lupus, and other diseases.


http://blogs.healthfreedomalliance.org/blog/2009/07/30/three-stage-vaccinations-may-create-perfect-cytokine-storm/


SQUALENE:

http://www.freerepublic.com/focus/f-news/2320188/posts

Squalene: The Swine Flu Vaccine’s Dirty Little Secret Exposed
Mercola.com ^ | July 18, 2009 | Dr. Mercola

Posted on Wednesday, August 19, 2009 10:10:32 PM by moonpie57

According to Kathleen Sebelius, Secretary of the U.S. Department of Health and Human Services, your children should be the first target for mass swine flu vaccinations when school starts this fall.

This is a ridiculous assumption for many reasons, not to mention extremely high risk.

(Excerpt) Read more at whale.to ...
TOPICS: Culture/Society; News/Current Events
KEYWORDS: h1n1; quack; swineflu; vaccine
What Squalene Does to Humans

Your immune system recognizes squalene as an oil molecule native to your body. It is found throughout your nervous system and brain. In fact, you can consume squalene in olive oil and not only will your immune system recognize it, you will also reap the benefits of its antioxidant properties.

The difference between “good” and “bad” squalene is the route by which it enters your body. Injection is an abnormal route of entry which incites your immune system to attack all the squalene in your body, not just the vaccine adjuvant.

Your immune system will attempt to destroy the molecule wherever it finds it, including in places where it occurs naturally, and where it is vital to the health of your nervous system.[viii]

Gulf War veterans with Gulf War Syndrome (GWS) received anthrax vaccines which contained squalene.[ix] MF59 (the Novartis squalene adjuvant) was an unapproved ingredient in experimental anthrax vaccines and has since been linked to the devastating autoimmune diseases suffered by countless Gulf War vets.

The Department of Defense made every attempt to deny that squalene was indeed an added contaminant in the anthrax vaccine administered to Persian Gulf war military personnel – deployed and non-deployed – as well as participants in the more recent Anthrax Vaccine Immunization Program (AVIP).

However, the FDA discovered the presence of squalene in certain lots of AVIP product. A test was developed to detect anti-squalene antibodies in GWS patients, and a clear link was established between the contaminated product and all the GWS sufferers who had been injected with the vaccine containing squalene.
1 posted on Wednesday, August 19, 2009 10:10:32 PM by moonpie57


Does Bill Kill?  

http://coupmedia.org/vaccinations/bill-gates-admits-vaccination-population-control-on-cnn-0703

Microsoft founder Bill Gates was recently interviewed by CNN Chief Medical Correspondent Sanjay Gupta. Gates was attending the World Economic Forum to push his mission of eradicating polio by 2012. Gates, through his foundation, has pledged $10 billion to provide vaccinations to children around the world .

In the course of the interview, in regards to the vaccine-autism connection, Gates said:

    "... t's an absolute lie that has killed thousands of kids. Because the mothers who heard that lie, many of them didn't have their kids take either pertussis or measles vaccine, and their children are dead today. And so the people who go and engage in those anti-vaccine efforts -- you know, they, they kill children. It's a very sad thing, because these vaccines are important."

How can someone so smart also be so confused about this issue? Unfortunately, that may actually be part of the problem.

Bill Gates may be one of the most destructive "do-gooders" on the planet because he is rich enough to get what he wants and he has a high opinion of his own intelligence. It is hard enough fighting Big Pharma, Big Government and Big Medicine on vaccines, but when another opponent is one of the wealthiest and most influential philanthropists in the world, it is even harder.

Fortunately, truth is more powerful than money. It is the only reason that the voices of parents and vaccine injured children continue to be heard above the relentless promotion of lies by the wealthy and powerful.

 

In this video below, Bill Gates makes more statements regarding the need for a population control program at the TED conference in Long Beach California in 2010.  Wait till he gets to 4 Minutes and 40 seconds into his speech.  Bill lets it slip again that if we do a really good job vaccinating people, we could lower population by 15%.

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Lorenzo's Oil and what is happening to the troops (and others!)
Similarities between ASD and ALD:

Adrenoleukodystrophy (ALD, also called Siemerling-Creutzfeldt Disease or Addison-Schilder's disease[1]:545) is a rare, inherited disorder that leads to progressive brain damage, failure of the adrenal glands and eventually death. ALD is a disease in a group of genetic disorders called leukodystrophies, whose chief feature is damage to myelin. In adrenoleukodystrophy, over-accumulation of VLCFAs leads to damage to the brain, adrenal gland, and peripheral nervous system on the age of onset of the disease. The classical, severe type is the childhood cerebral form which, as an X-linked disease, affects males. Symptoms normally start between the ages of 4 and 10 and include loss of previously acquired neurologic abilities, seizures, ataxia, Addison's disease, and degeneration of visual and auditory function. It has been seen that infants that have been positively diagnosed by the age of 1 year old have usually become very ill by the age of 10 to 12 years and die soon after. This severe form of the disease was first described by Ernst Siemerling and Hans Gerhard Creutzfeldt.[2] A similar form can also occur in adolescents and very rarely in adults. Addison's disease can be an initial symptom of ALD, and many pediatric endocrinologists will measure very long chain free fatty acids in newly diagnosed males with this condition, as a screening test for ALD.
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Are ASD and ALD the same animal in different sizes?

https://www.explorepub.com/sample-articles/60-medical-breakthroughschildren/217-essential-fatty-acids-lorenzos-oil-and-beyond-.html

Essential Fatty Acids, Lorenzo's Oil and Beyond
©Copyright 1997 by Patricia Kane, Ph.D., Millville, New Jersey, U.S.A.

(Explore Issue: Volume 7, Number 6)

With the birth of their beautiful baby boy, Stephen and Rebecca Vaughn were overjoyed and meticulously recorded through pictures, video and diaries every nuance of his developement. After an anaphylactic reaction to a routine MMR (measles-mumps-ruebella) vaccination Alex emotionally began to slip away into a world of his own. Due to Alex's close bond with his parents they noticed the change in his behavior and desperately tried to lovingly engage him in play and interaction with others, but one month passed his second birthday Alex was diagnosed with autism. Medical science has failed to determine the cause of autism, but we do know through specialized testing that the impact is systemic-affecting every system of the body.

kane.alexAlex Vaughn

For Alex and two hundred other children whose blood chemistries and red cell membrane fatty acids we have thoroughly researched, there is gross aberration in the fatty acid metabolism and the electrolyte status of children and adults not only with autism but with seizure activity, developmental delay, traumatic brain injury and cerebral palsy. Alex's parents were determined to save their precious little boy. They began metabolic intervention within two months of his diagnosis.

The first course of action for Alex's condition was to obtain a complete blood chemistry (Chem-28 including a CO2 and CBC with diff) and enter the results into the BodyBio data management system. The unique patterns of disturbances within Alex's biochemistry were boldly demonstrated and a course of treatment through metabolic intervention began as the suggestions within the system are all based upon peer reviewed medical articles. The strength of their application comes from the specificity to the undividual patient and the depth of the research substantuating the findings.

bloodtextalexSample of Alex Vaughn's blood test

Alex had a serious disturbance in his electrolyte status (deep depression of sodium and carbon dioxide), profoundly altered nitrogen status involving every nitrogen marker, sharply altered hematology and skewed differential. Carbon Based analysis is cross referenced with an enormous data base that matches nutrients to alterations in blood chemistry in regard to specific nutrient need. There are, for example, ten different forms of magnesium in the BodyBio system as chloride, malate, sulfate, taurate, carbonate, salicilate, aspartate, lactate, glycinate, and citrate. These bonding angles on magnesium are just as important as the base metal magnesium and they are defined specifically in Alex's chemistry.

Alex's chemistry revealed that he needed magnesium carbonate/magnesium malate and along with an entire roster of nutrients (ammonium molybdate, inositol, ascorbate, Vitamin K, pyridoxine, niacinamide, biotin, lactoferrin, plant enzymes, zinc citrate, oral electrolytes, N-acetyl glucosamine, ferritin, creatine, pantethine, riboflavin-5-phosphate, folinic acid, free form amino acids, adenosylcobalamin, inosine, carnitine, multivitamin formula, salivarius, plantarum, ionic liquid minerals, aqueous liver concentrate, Bromelain, Viobin Prometol, Omega Nutrition coconut butter and sesame oil, sesamin, and liquid colostrum). With a complete revision of his diet (high nutrient density, removal of gluten and casein, carb-protein-fatty acid balanced meals and snacks) the Vaughn family began to fight back against the autism.

Within three months of nutritional support Alex went from a complete absence of speech to four dozen words! Alex's father, Stephen, would call weekly with updates on his son's progress almost shouting his excitement in the tremendous gains Alex made in social interaction, eye contact, imaginative play, general health, physical movement, speech and began to ask for and consume concentrated protein foods.

After eight months of nutritional intervention Alex returned for re-evaluation to the physician who had made his original diagnosis. The doctor was awestruck as he examined Alex and observed him laughing and playing and talking -- he stated that he had not seen a child with autism change so drastically in 17 years of practice. Alex was chosen by the Miracle Children's Network to appear on television as the poster boy in June of 1996. While posing for pictures for the event Alex firmly held up his arms and said, "I am Awesome Alex -- The Adventurer!!!"

As so many families agonize over treatment for intractable seizure disorders, developmental delay, disturbances in metabolism, autism, traumatic brain injury and neurodegenerative conditions they often find twisted, frustrating pathways that lead to more questions than answers for their critically ill loved ones. Often the label genetic defect or inborn error in metabolism etiology unknown is solidly placed upon children and adults who fail to conform to a rigid set of parameters that define a particular disorder or disease. The true query is: What shall we do now to address metabolic disturbances in the myriad of "hopeless" conditions that exist today? These are real children and adults that are being further damaged every day. They are frequently told to wait for the drug or gene therapy that will be the answer to their health condition. It will be a very long wait, too long for most unfortunately. Often the media focuses on a family who is fighting for their child such as Michaela and Augusto Odone who tried to find a treatment for their child with adrenoleukodystrophy (ALD) with the use of Lorenzo's Oil.

[global_fiefdom]

Lorenzo Odone

The story of Lorenzo, who is now 17 years old, is sadly not a successful one. Medical trials have proven that the elevation of very long chain saturated fatty acids (C24:O lignoceric acid and C26:O hexacosanoic) are normalized with the administration of Lorenzo's Oil (C18:1 oleic acid and C22:1 erucic acid) but the degeneration of the condition persists and is relentless. Use of the oil causes gross deficiency of omega 3 and omega 6 fatty acids and lowers the platelet count. Amazingly, researchers have finally (we pointed out the association of omega 3 and omega 6 fatty acids years ago but it was ignored) now discovered that children with adrenoleukodystrophy are deficient in docasahexaenoic acid (DHA) and are conducting trials on the administration of this fatty acid derived from algae (Martek Biosciences Corporation). DHA is available in marine oils but due to the fishy taste researchers shunned using it due to difficulties with patient compliance. It is crucial that medical testing of red cell membrane fatty acids be performed so that application of therapy is specific to the individual's requirements. Children with adrenoleukodystrophy have low docasahexaenoic acid, low nervonic acid and high lignoceric acid while children with autism, seizures and brain injury also may exhibit high lignoceric acid but have high docasahexaenoic acid and high nervonic acid. Arbitrary administration of specialized fatty acids is inappropriate due to the unique patterns of fatty acid derangement in specific medical conditions.

kane.charlieCharlie Abrahams

The movie producer Jim Abrahams spoke out publically when his son Charlie responded positively to the ketogenic diet (low carbohydrate, high fat) at Johns Hopkins. Charlie had suffered from an especially difficult form of epilepsy, Lennox-Gastaut syndrome, characterized by numerous types of seizures and often unresponsive to anticonvulsant medication. After $100,000 worth of tests, drugs and surgery the convulsions continued to rack Charlie's body 100 times a day. In desperation Jim went to the medical library in search of an answer and found the book Seizures and Epilepsy in Childhood: A guide for Parents by Dr. John M. Freeman. Charlie was one of the lucky 30% of children whose seizures stopped on the ketogenic diet and he remained seizure free until the diet was stopped. After two years when the diet was discarded, the seizures returned with a vengeance and are now intractable. Dr. Freeman states that he does not know the reason that the ketogenic diet works -- or does not work. This is not surprizing since many clinicians do not have time to view the medical literature and blend their findings with that of other researchers.

The biochemical basis for the success of the ketogenic diet is simple. The cessation of eating stimulates the beta oxidation of very long chain fatty acids that not only occurs in adrenoleukodystrophy but in epilepsy, autism and developmental delay. The ingestion of carbohydrate also stimulates the release of insulin which depresses delta 6 desaturase and stimulates inflammatory prostaglandin two series and ultimately causes derangement of the fatty acid metabolism. Excess carbohydrate ingestion, which is so common in our present American diet, diverts and compromises the synthesis of prostaglandin series one. The modulation of fatty acid metabolism, however, is quite complicated and the lack of knowledge in regard to the coenzymes, the individual child's metabolism, the balance of electrolytes and the recent addition of hydrogenated fats to the ketogenic diet makes the outcome of this treatment shaky at best.

The Odone's and Abrahams' as well as many, many parents have been through excruciatingly painful ordeals with their children and have searched the ends of the earth to come up with treatments that would relieve their child's suffering. Often there is a promise of hope if the child stabilizes with a manipulation of the fatty acid metabolism but lack of knowlege of fatty acid metablism has grossly hindered our progress in treatment of neurodegenerative conditions.

In our struggle to direct the biochemistry of the human system we have fallen into an abyss in regard to our understanding of lipids and therapeutic manipulation. Virtually every aspect of metabolism is completely dependent upon the fats we consume yet current opinion leads one to believe that the etiology of the catastrophic illnesses of our time all have an intimate connection to the consumption of butter, eggs and meat. The entire spectrum of autoimmune disorders, endocrine imbalances, gastrointestinal disturbances cardiovascular difficulties and central nervous system involvement are all rivoted in derangement of fatty acid metabolism. The conflict is so deep that cardiologists and oncologists have completely opposing statements in regard to lipid consumption, one stating that fats be avoided completely and the other the exclusive use of polyunsaturated fats. American and European homes abound with polyunsaturates, unfortunately they are in the form of hydrogenated or trans fatty acids that are lifeless lipids that cannot support nutriture with anything more than calories. The use of trans fats literally shuts down the fatty acid metabolism. The synthesis of prostaglandins-local hormones that control all cell to cell interactions within the body-are completely dependent upon the ingestion of high quality, unaltered fatty acids. The body requires specific fatty acids to create gastrointestinal integrity, bilipid membranes, hormones, neurohormones, prostaglandins and immune modulators all derived from fatty acids and these fats must be supplied and trans fats avoided if modulation of the faulty metabolism is to be achieved.

Troops suffering Lipid alterations?

CHRONIC FATIGUE AND DAMAGED MITOCHONDRIA/LIPIDS, LIPID REPLACEMENT DIET:

Chronic Fatigue Illnesses

Prof. Garth L. Nicolson

Chronic Fatigue Syndrome, Fibromyalgia Syndrome and Other Fatigue Conditions

Chronic fatigue is reported by 20% of all patients seeking medical care and is considered as a nonspecific sign that is associated with many well known medical conditions. Chronic Fatigue Syndrome (CFS), Myalgic Encephalomyelitis (ME), and Fibromyalgia Syndrome (FMS) patients suffer from complex overlapping signs and symptoms. (see 'Signs/Symptoms' Questions, above) CFS is primarily characterized by persisting or relapsing fatigue without previous history of comparable symptoms that does not resolve with rest. In these patients other clinical conditions are absent that can explain the signs and symptoms such as malignancies or autoimmune diseases. In contrast, FMS patients have overall muscle pain, tenderness, and weakness as primary complaints, but they have most if not all of the commonly found signs and symptoms for CFS. We previously proposed that CFS/ME patients might be suffering from chronic infections that can cause, in part, their complex signs and symptoms. For example, systemic mycoplasmal infections can cause chronic fatigue, muscle pain and a variety of additional signs and symptoms, some of which are related to dysfunctional immune responses and in extreme cases autoimmune-like disorders. Some mycoplasmas can invade virtually every human tissue and can compromise the immune system, permitting opportunistic infections by other bacteria, viruses, fungi and yeast. When mycoplasmas exit certain cells, such as synovial cells, nerve cells, among others that can be infected, they can stimulate autoimmune response. Our recently published studies demonstrated a possible link between mycoplasmal infections and CFS and FMS, since we found high frequencies of mycoplasmal infections in these patients. Previously we examined patients with chronic illnesses for the presence of mycoplasmal infections. We found that about one half of patients with Gulf War Illness and two third of patients with CFS/ME and FMS were positive for mycoplasmal infections in their blood. The Gulf War Veterans suffer from signs and symptoms similar to patients diagnosed with CFS and FMS. They can be treated using antibiotics effective against mycoplasmal infections, and once they recover, their blood is no longer positive for the presence of mycoplasmal infections. Our recent results indicate that Rheumatoid Arthritis is also associated with mycoplasmal infections. (see 'Autoimmune Diseases')

Recent reports and publications indicate that in addition to mycoplasmal infections, CFS/ME and FMS patients have other chronic infections caused by other intracellular bacteria and viruses. For example, patients with Lyme Disease, caused by intracellular Borrelia infections, have been diagnosed with CFS/ME. Also, CFS/ME and FMS patients can have intracellular Chlamydia species infections. These patients can also have infections by other bacteria that enter their bodies through 'leaky gut' problems. Chronically ill patients often have inflammatory bowel syndrome and other gut problems, and this can allow pathogenic bacteria to enter their systems.

Patients with CFS/ME and FMS can also have viral infections that complicate their conditions and cause morbidity. Such infections can occur with or without the bacterial infections described above. Viruses that have been associated with CFS/ME and FMS are Human Herpes Virus-6 (HHV-6) and Cytomeglovirus (CMV). These viruses have been found at high incidence in chronically ill patients, and especially those with CFS/ME. Patients with CFS/ME or FMS can have predominantly intracellular bacterial infections, predominantly viral infections, or a combination of intracellular bacterial and viral infections. This may be one reason why the underlying causes of these chronic illnesses are so difficult to determine and effectively treat. The other reason could be the persistent nature of the infections and their ability to hide inside cells where they are essentially refractory to immune system responses, their slow growing natures and their relative insensitivity to therapeutic drugs (see references below).

A new direction at the Institute is studying the role of decreased cellular energy in causing fatigue.  Cellular energy is mainly produced by the mitochondria, subcellular organelles that contain the machinery that converts fats and sugars to energy in the form of the high-energy molecules, such as ATP.  Mitochondrial function requires an intact inner membrane where the electron transport chain or energy machinery is located.  When the inner mitochondrial membrane is damaged, the efficiency of the electron transport chain is reduced along with the ability of cells to produce the energy that they need for vital functions—thus fatigue becomes a problem.   Various environmental insults and even aging produce excess oxidation molecules that can damage the mitochondrial membrane, including chronic infections of the type mentioned above.  At the Institute for Molecular Medicine clinical studies have shown the benefits of dietary membrane lipids (Lipid Replacement Therapy) in replacing damaged mitochondrial membrane lipids, increasing the efficiency of the electron transport chain, increasing energy and reducing fatigue.  A number of non-pharmaceutical approaches to decreasing fatigue are being investigated at the Institute.

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FAT IS YOUR BEST FRIEND

Mediterranean Diet best for recovery of autistic and GWS victims of vaccine damage?

http://en.wikipedia.org/wiki/Mediterranean_diet

The Mediterranean diet is a modern nutritional recommendation inspired by the traditional dietary patterns of southern Italy, Crete and much of the rest of Greece in the 1960s.[1]

On November 17, 2010, UNESCO recognized this diet pattern as an Intangible Cultural Heritage of Italy, Greece, Spain and Morocco, thus reinforcing it not only as a fundamental part of their history and background, but also as a great contribution to the world.[2]Despite its name, this diet is not typical of all Mediterranean cuisine. In Northern Italy, for instance, lard and butter are commonly used in cooking, and olive oil is reserved for dressing salads and cooked vegetables.[3] In North Africa, wine is traditionally avoided by Muslims. In both North Africa and the Levant, along with olive oil, sheep's tail fat and rendered butter (samna) are traditional staple fats.[4]

The most commonly understood version of the Mediterranean diet was presented, amongst others, by Dr Walter Willett of Harvard University's School of Public Health from the mid-1990s on,[5][6][7][8][9] including a book for the general public.[10] Based on "food patterns typical of Crete, much of the rest of Greece, and southern Italy in the early 1960s", this diet, in addition to "regular physical activity," emphasizes "abundant plant foods, fresh fruit as the typical daily dessert, olive oil as the principal source of fat, dairy products (principally cheese and yogurt), and fish and poultry consumed in low to moderate amounts, zero to four eggs consumed weekly, red meat consumed in low amounts, and wine consumed in low to moderate amounts". Total fat in this diet is 25% to 35% of calories, with saturated fat at 8% or less of calories.[11]

The principal aspects of this diet include high olive oil consumption, high consumption of legumes, high consumption of unrefined cereals, high consumption of fruits, high consumption of vegetables, moderate consumption of dairy products (mostly as cheese and yogurt), moderate to high consumption of fish, low consumption of meat and meat products, and moderate wine consumption.[12]

Olive oil is particularly characteristic of the Mediterranean diet. It contains a very high level of monounsaturated fats, most notably oleic acid, which epidemiological studies suggest may be linked to a reduction in coronary heart disease risk.[13] There is also evidence that the antioxidants in olive oil improve cholesterol regulation and LDL cholesterol reduction, and that it has other anti-inflammatory and anti-hypertensive effects.[14]

[global_fiefdom]

The MTOR Pathway

Targeting mTOR pathways — dangerous HIV vaccine adjuvant (vaccines are directly related to autism in many cases — history will vindicate this claim):

http://www.experts.scival.com/georgia/grantDetail.asp?t=ep1&id=8854548&o_id=83&

    Targeting mTOR and CD40 Pathways for Adjuvanting HIV Vaccines

    Amara, Rama Rao

    1 June 2010 – 31 May 2013
    NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
    Total Funding: $ 2,440,751

    Abstract Development of an effective HIV vaccine is the long-term solution to control HIV/AIDS world-wide. The failure of adenovirus type 5 based HIV-1 vaccines in humans that was designed to elicit primarily antiviral T cells strongly suggests the need to develop novel vaccine approaches that generate high levels of antiviral T cells with improved function as well as protective antibody. Development of novel adjuvants is necessary to enhance the immunogenicity and efficacy of HIV vaccines. In this HIVRAD, we will use molecules that target mTOR (mammalian target of rapamycin) and CD40 pathways as novel adjuvants to elicit high levels of polyfunctional virus-specific CD8 T cells, CD4 T cells that are resistant to HIV infection and high avidity protective antibody that will lead to enhanced control of HIV infection.
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http://blog.cent4dent.com/category/vaccines-and-autism/

    Sahin hopes that the brain’s miswiring can be corrected by drugs targeting the molecular pathways that cause it. The mTOR pathway is emerging as central to various kinds of axon abnormalities, and drugs inhibiting mTOR has already been approved by the FDA. For example, one mTOR inhibitor, rapamycin, is currently used mainly to prevent organ rejection in transplant patients, and Sahin plans to launch a clinical trial of a rapamycin-like drug in approximately 50 patients with TSC later this year, to see if the drug improves neurocognition, autism and seizures.

THEY HAVE TO STOP ADJUVATING THE f**kING VACCINES…

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Link between autism muscle tone and diabetes blood sugar cycle through mTOR pathway:




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Lucrative Human Experimentation/Research on Spinal Cord Regeneration for Wealthy Clients Behind Some of the Vaccine Ingredients Given to Us Today?
We the People Refuse to be Lab Monkeys for the NWO!

In breakthrough, nerve connections are regenerated after spinal cord injury

Posted by Xeno on August 8, 2010

    Researchers for the first time have induced robust regeneration of nerve connections that control voluntary movement after spinal cord injury, showing the potential for new therapeutic approaches to paralysis and other motor function impairments.

    In a study on rodents, the UC Irvine, UC San Diego and Harvard University team achieved this breakthrough by turning back the developmental clock in a molecular pathway critical for the growth of corticospinal tract nerve connections.

    They did this by deleting an enzyme called PTEN (a phosphatase and tensin homolog), which controls a molecular pathway called mTOR that is a key regulator of cell growth. PTEN activity is low early during development, allowing cell proliferation. PTEN then turns on when growth is completed, inhibiting mTOR and precluding any ability to regenerate.

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How do they stop the nerve and brain cells from multiplying? Once you receive a stem cell transfusion, how does your adult body know how to regulate what happens to those cells? Could you die of cranial compression like the young man in my uncle's prophetic book about bio-engineering, "Cat Game"?



http://www.medicalnewstoday.com/releases/47193.php

Autism May Involve A Lack Of Connections And Coordination In Separate Areas Of The Brain, Researchers Find
Main Category: Autism
Article Date: 16 Jul 2006 - 7:00 PDT

Researchers have found in two studies that autism may involve a lack of connections and coordination in separate areas of the brain.

In people with autism, the brain areas that perform complex analysis appear less likely to work together during problem solving tasks than in people who do not have the disorder, report researchers working in a network funded by the National Institutes of Health. The researchers found that communications between these higher-order centers in the brains of people with autism appear to be directly related to the thickness of the anatomical connections between them.

In a separate report, the same research team found that, in people with autism, brain areas normally associated with visual tasks also appear to be active during language-related tasks, providing evidence to explain a bias towards visual thinking common in autism.

The researchers made another discovery, for the first time finding a relationship between this lower level of synchrony and the properties of some of the neurological "cables" or white matter fiber tracts that connect brain areas.

White matter consists of fibers that, like cabling, connect brain areas. The largest of the white matter tracts is known as the corpus callosum, which allows communication between the two hemispheres (halves) of the brain.
"The size of the corpus callosum was smaller in the group with autism, suggesting that inter-regional brain cabling is disrupted in autism," Dr. Just said.

In essence, the extent to which the two key brain areas (prefrontal and parietal) of the autistic participants worked in synchrony was correlated with the size of the corpus callosum. The smaller the corpus callosum, the less likely the two areas were to function in synchrony. In the normal participants, however, the size of the corpus callosum did not appear to be correlated with the ability of the two areas to work in synchrony.

"This finding provides strong evidence that autism is a disorder involving the biological connections and the coordination of processing between brain areas," Dr. Just said.

He added, however, that the thickness, or extent, of connections between brain areas may not be the basis for the disorder. Although the neurological connections between the prefrontal cortex appear to be reduced in autism, the brains of people with autism have thicker connections between certain brain regions within each hemisphere.
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Vaccines causing Corpus Callosum, the largest myelinated area of the brain, to become stripped of its coating..?

http://www.healing-arts.org/children/vaccines/vaccines-auto-immunity.htm

A cause and effect relationship between antibodies to myelin basic protein (MBP) and autism has not yet been definitively established. There may be many routes to autism, of which auto-immunity is only one. Nevertheless, the development of antibodies to MBP may be a major route through which vaccination contributes to autism.

Another possibility for post-vaccine related damage is delayed or incomplete myelination in the corpus callosum (the largest myelinated area of the brain), which has been suggested as a basis for auditory processing problems in some children with learning disabilities (LD).23 Immunological assaults from wild virus infection or vaccine virus infection could theoretically result in poor myelination or abnormal function of the neuron-axon myelin.

[global_fiefdom]

Medical site admitting too many stem cells being injected at once can cause "risk of encephalopathy":

http://www.stemcellshezhong.com/qa.asp

15. For Batten disease treatment, I want to know the type of stem cells being used? How many cells? Is there a reason the number of cells can��t be increased? It is my understanding that in the Stem Cells Inc., trial for Batten disease the last 5 patients received 1 Billion purified neural stem cells. Little improvement was observed. The patients were stabilized for a time but improvement was minimal. 20 Million is 2% of the cells used in the US trial, why are these numbers so different?

For the treatment of Batten disease, our doctors prefer to use neural stem cells, and in the treatment procedure, there are 4 separate stem cell injections (once per week) with 5 million stem cells in each injection. According to our clinical research and laboratory tests an individual can only handle a limited number of stem cells from external sources effectively. For children suffering from Batten disease, 5 million stem cells in each injection is the most effective number. If we implanted more stem cells into the patient's body there would be no improvement but it would add to the cost and more importantly, it would add a risk of developing encephalitis and other side effects.

[global_fiefdom]

PTEN developed at expense of millions of innocent children who received dangerous vaccine adjuvants and potentially fetal stem cells from aborted fetuses?

http://www.msrc.co.uk/index.cfm/fuseaction/show/pageid/1826

"We reconstituted single stem cells' family trees to look at the progeny they gave rise to," says Guo-li Ming, associate professor of neurology and neuroscience and a member of the Neuroregeneration Program in the Institute for Cell Engineering. "We discovered that single cells in an intact animal nervous system absolutely do exhibit stem-cell properties; they are capable of both replicating themselves and producing different types of differentiated neural progeny."

The team followed the fates of all the marked radial glia-like stem cells for at least a month or two, and examined some a full year later to discover that even over the long term, the "mother" cell was still generating itself as well as different kinds of progeny.

In addition, the researchers investigated how these RGLs were activated on a molecular level, focusing, in particular, on the regulatory role of an autism-associated gene called PTEN. Conventional wisdom was that deleting this gene led to an increase in stem-cell activation. However, the scientists demonstrated that was a transient effect in the mouse brains, and that, ultimately, PTEN deletion leads to stem-cell depletion.

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Opposite Effects of HIV-1 p17 Variants on PTEN Activation and Cell Growth in B Cells
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0017831

Cinzia Giagulli1#, Stefania Marsico2#, Anna K. Magiera3, Rosalinda Bruno2, Francesca Caccuri1, Ines Barone4, Simona Fiorentini1, Sebastiano Andò4, Arnaldo Caruso1*

1 Department of Experimental and Applied Medicine, University of Brescia, Brescia, Italy, 2 Department of Pharmaco-Biology, University of Calabria, Arcavacata di Rende (Cosenza), Italy, 3 Medestea Research, Turin, Italy, 4 Department of Cell Biology, University of Calabria, Arcavacata di Rende (Cosenza), Italy
Abstract Top

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Study links loss of PTEN gene with patient's response to melanoma therapy
Published on June 4, 2011 at 8:03 AM · No Comments

    inShare1

Genetic analysis of the tumors from patients with advanced melanoma can clue researchers in to how well patients will respond to a therapy that targets the growth-promoting protein called BRAF, a researcher from the Perelman School of Medicine at the University of Pennsylvania will report on Monday, June 6 at the annual meeting of the American Society of Clinical Oncology. Looking outside of the BRAF gene, the researchers found loss of the tumor suppressor gene PTEN also appears to be associated with patient response to GSK436, which could help guide researchers to even more personalized approaches to melanoma therapy.

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http://www.biologynews.net/archives/2011/05/03/protein_identified_as_enemy_of_vital_tumor_suppressor_pten.html

A protein known as WWP2 appears to play a key role in tumor survival, a research team headed by a scientist at The University of Texas MD Anderson Cancer Center reports in an advance online publication of Nature Cell Biology.

Their research suggests that the little-studied protein binds to the tumor-suppressing protein PTEN (phosphatase and tensin homologue deleted on chromosome 10), marking it for destruction by proteasomes, which degrade proteins and recycle their components.

PTEN plays a role regulating the cellular reproduction cycle and prevents rapid cell growth, a hallmark of malignant cells. Its gene is mutated or deleted in many types of cancer, the researchers noted.

The WWP2 (atrophin-1 interacting protein 2) protein was discovered in the laboratory of Junjie Chen, Ph.D., professor and chair in MD Anderson's Department of Experimental Radiation Oncology and senior author of the paper.

"We were trying to find regulators of PTEN when we isolated the protein WWP2 as a putative PTEN-associated protein," Chen said. He noted that WWP2 caught the researchers' attention because it is similar to the NEDD4-1 protein, which has been proposed as a regulator of PTEN function.
The HIV-1 matrix protein p17 is a structural protein that can act in the extracellular environment to deregulate several functions of immune cells, through the interaction of its NH2-terminal region with a cellular surface receptor (p17R). The intracellular events triggered by p17/p17R interaction have been not completely characterized yet. In this study we analyze the signal transduction pathways induced by p17/p17R interaction and show that in Raji cells, a human B cell line stably expressing p17R on its surface, p17 induces a transient activation of the transcriptional factor AP-1. Moreover, it was found to upregulate pERK1/2 and downregulate pAkt, which are the major intracellular signalling components involved in AP-1 activation. These effects are mediated by the COOH-terminal region of p17, which displays the capability of keeping PTEN, a phosphatase that regulates the PI3K/Akt pathway, in an active state through the serin/threonin (Ser/Thr) kinase ROCK. Indeed, the COOH-terminal truncated form of p17 (p17Δ36) induced activation of the PI3K/Akt pathway by maintaining PTEN in an inactive phosphorylated form. Interestingly, we show that among different p17s, a variant derived from a Ugandan HIV-1 strain, named S75X, triggers an activation of PI3K/Akt signalling pathway, and leads to an increased B cell proliferation and malignant transformation. In summary, this study shows the role of the COOH-terminal region in modulating the p17 signalling pathways so highlighting the complexity of p17 binding to and signalling through its receptor(s). Moreover, it provides the first evidence on the presence of a p17 natural variant mimicking the p17Δ36-induced signalling in B cells and displaying the capacity of promoting B cell growth and tumorigenesis.
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WWP2 Weaponized?

Could lead to the development of new drugs for aggressive cancers within the next decade

University of East Anglia researchers may have found a way to prevent the spread of cancer through the discovery of a rogue gene.

Andrew Chantry, study leader from the University of East Anglia's School of Biological Sciences, and Dr. Surinder Soond, of the University of East Anglia, have discovered a rogue gene that, if blocked by proper medication, could prevent the spread of cancer.

The discovery of the rogue gene came about when the team of researchers was studying 'Smads,' which are natural cancer cell inhibitors in the human body.

The rogue gene is called WWP2, and it is an enzymic bonding agent. It is found within cancer cells and helps the spread of cancer by attacking Smads in the human body, which are supposed to stop the spread of cancer.

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Bill Clinton Tested AIDS Vaccines on Unwitting Troops!

ANTHRAX VACCINE: CURE OR CONSPIRACY?

 

An interview with Dr. Leonard Horowitz, Dec. 18, 1997

By Wes Thomas, moderator, BIOWAR-L

 

Dr. Horowitz is author of Emerging Viruses: AIDS & Ebola [1], a comprehensive, well-documented exposé of the role of tainted vaccines in the creation of genocidal AIDS and Ebola epidemics. He holds a Ph.D. in dental medicine from Tufts University, Master of Public Health from Harvard University, and MA in health education from Beacon College.

 

WT: There's a lot of paranoia on the Net right now about anthrax vaccine. Should people take it or not?

LH: Well, President Clinton won't take the vaccine [2] because he's no fool. I'm extremely concerned that anthrax vaccine is untrustworthy and that military personnel, when they sign up, turn their lives over to untrustworthy people. You'd have to be a fool, given the information we have in our possession, to take the anthrax vaccine, or any other vaccine that the FDA and/or the Department of Defense approves or tries to push on military personnel or citizens of the United States.

WT: Why?

LH: Numerous reasons. Everything from the most apparently benign vaccine to the tetanus vaccine used to sterilize hundreds of thousands of women during experiments, to Gulf War Syndrome, which is undoubtedly related and linked to vaccines.

We now have evidence that the potential initiator of Gulf War Syndrome was an AIDS vaccine that was being tested on uninformed and unconsenting troops. We have documentation that shows that General Schwartzkopf and General Powell were absolute outrageous liars in the congressional hearing statements and that the entire Gulf War congressional investigating panel, led by Jay Rockefeller, was a complete travesty to truth and justice.

We have this documentation on a new three-hour video called "Gulf War Syndrome: the Spreading Epidemic Cover-up" [3]. It shows that during the Gulf War, our troops were exposed to experimental vaccines and experimental drugs, that sustained drug interactions and vaccine damage were the result, and that the federal government still refuses to acknowledge the truth and the facts.

In no uncertain terms would I allow myself to be inoculated, nor would any rational human being, given the evidence. Which is the real intelligent reason why President Clinton has refused to be vaccinated with anthrax vaccine. So as Commander in Chief of the military he would allow his military personnel to be vaccinated when he himself has refused!

WT: USAMRIID [U.S. Army Medical Research Institute of Infectious Diseases] has stated [4] that "there are insufficient data regarding efficacy against inhalation anthrax in humans, although studies in rhesus monkeys indicate it is protective" and Senate Report 103-97 [13] agreed. So why is the military administering it?

LH: Good question. Anthrax has been a fairly easy-to-reproduce microorganism that lots of people have capability of reproducing and spreading. Why all of a sudden would the Pentagon reverse its long-held position that it should not be administered? Haven't they learned enough from the Gulf War Syndrome?

WT: What evidence do you have that anthrax vaccine is contaminated?

LH: Look at all the vaccines. For example, the Clinton administration has stated that it's mandatory that 12-hour-old infants get hepatitis B vaccine. This is insane. It has no risk/benefit analysis done to it. We don't know if this vaccine is killing and maiming more people than it's helping. Besides the fact that this particular vaccine has carcinogenic enzymes in it, it doesn't make any sense whatsoever to give it to infants, because 96 percent plus of the people who get hepatitis B get it through sexual transmission or IV drug use. Plus the fact that those who get it develop life-long immunity and they do not develop major long-term problems.

The issue becomes how many people are being harmed by getting these vaccines. According to the CDC's own data [1], potentially 25,000 to 35,000 people were injured from that one vaccine. And consider all 18 or so vaccines that the federal government now is allegedly mandating (you still have religious and spiritual exemptions, so it's really against your civil rights to be told you must get a vaccine for school or work). If you use the CDC's own data, your find you have an ongoing holocaust of vaccine-induced injuries to the tune of as many as 800,000 vaccine-induced injuries occurring every year in the United States that you don't hear a word about from the federal government or mainstream media. So isn't that strange?

But today in the newspaper you do hear that the federal government wants to reevaluate nutritional supplements because three college wrestlers died of taking hormones. And yet we have 800,000 people sustaining vaccine-induced injuries, and you don't hear a word about it. If you don't think, given that information, that there's a covert operation here or an alternative agenda here...

WT: What's the agenda?

LH: According to top military personnel that I've interviewed from the Pentagon, the apparent agenda is a new world order where a strong U.S. military represents a liability.

WT: Sounds crazy. Why would they jeopardize their own troops?

LH: Because if you have rah-rah American patriotic military people who are stockpiling weapons and these people are healthy, happy, and prosperous, and you tell them "No, you've got to put down your guns and give up your national sovereignty and take orders from U.N. peacekeeping officials, and NATO Alliance officers," and soldiers are asked whether they'd be willing to shoot on American citizens before they give them a gun .... It may sound like foolish conspiratorial nonsense, until you evaluate you who this information is coming from: the senior Pentagon officials I've interviewed who take this threat seriously.

WT: Richard Preston [author, The Cobra Event] recently said [5] the Russians are actively developing advanced, genetically-engineered bioweapons and working with the Club Mad rogue nations  and Jane's Defense Weekly [11] just announced that Russia has developed a highly contagious super black plague. Aren't those realistic external threats?

LH: The Russians had the capabilities for doing this for years, so when you read these press reports, what are they really telling you that's new? They're telling you propaganda. What's the motivation behind the news? It's persuasion. Look at the motive behind the persuasion, and what is it? They're preparing us for biological holocaust and they're going to blame it on the Muslims, Christian patriots, and militia groups. The militia groups are already dysfunctional because they're penetrated by agitators.

Interesting that our good old friend Larry Wayne Harris [6] is again in the center of this controversy. He alleges to be a Christian and patriot, and yet he goes to the Preparedness Expositions and shows the hardware to produce and disperse the bioweapons and tells you and writes [7] how to go out and produce these bioweapons and distribute them. This man acknowledges being a CIA operative, acknowledges having friends from the CIA that feed him, alleges he was involved with the CDC.

American intelligence officials are seeding authors, reporters, and investigative journalists, saying that it's the Christian patriots who are now the ones who are suspected of being the future terrorists in bioweapons attacks. If this isn't an obvious setup, my name isn't Len Horowitz. Harris is setting up the Christian and patriot movements to be the fall guys for the most untrustworthy people who are in charge of these bioweapons.

When you look at the videotape [Gulf War Syndrome: the Spreading Epidemic Cover-up], you see that we -- the U.S. government and our companies -- supplied Saddam Hussein with biological and chemical weapons at least up until two weeks before he invaded Kuwait [8]. And now there's some evidence that Joyce Riley [9] cites that he may have even been getting these during the war.

WT: What do you know about Michigan Biologic Products Labs, the sole supplier of anthrax vaccine to the military?

LH: Look for links to I. G. Farben, George Bush, and the Nazis. It's seldom I don't find that those who are suspected of foul play are not led by the people or their heirs who were intimately involved in the biological weapons industry under Hitler and that we in the U.S. were literally partners with those people. I'm speaking about the well-documented historical partnership between I.G. Farben, Bayer, Merck & Co, and the Rockefellers [1].

In fact, the president of Merck, George W. Merck, was America's biological weapons industry director, personally appointed by President Roosevelt and Secretary of War Stinson in the early 1940s. And in 1945, when Hitler realized he was going to lose the war, he ordered Martin Bormann, the Third Reich's economic chief, to bury his war chest to assure Germany's economic recovery after WW II, but also to assure a virtual monopoly over the world's pharmaceutical and chemical industries and the "rise of the Fourth Reich." Much of that money went into Merck & Co.

Now this at the exact time that George W. Merck is advising President Roosevelt on America's biological weapons status, as director of the industry. And follow the history of those Nazis, including Erik Traub, Hitler's top bioweapons developer -- who was brought over by Henry Kissinger and General Bolling in Project Paperclip -- and the exportation of 2000 Nazis into the U.S. industrial and intelligence organizations. And Traub went to work for the U.S. Navy biological research lab, which is affiliated with many of the academic institutions in the U.S. that are the premier biological weapons development and testing operations.

You have to begin to see that there is a whole underlying network of extraordinarily wealthy individuals, in fact, who have an ideology for population reduction, and specifically, the Merck company's fund as well as the Rockefeller Foundation, two of the premier American population control funding agencies. And when you see that these people are multinational supporters, and you understand that their ideology for population reduction follows the same reasoning that Hitler followed with racial hygiene: to make it American intelligence's and national security's primary interest for foreign policy.

This policy was funded by Prescott Bush (George Bush's father), General William Draper, and the Rockefellers -- the first people in the congress in 1968 that came out in favor of population reduction in the third world -- and translated into legislation by Henry Kissinger in National Security Memorandum 200, penned in 1971.

So you begin to see that these are the same people with the same agenda and the same money. And far more money because they've invested it all those years. And today's history that is unfolding before our eyes is a repeat.

WT: According to the U.S. Army Medical, Chemical, and Biological Defense Program [10] the Anthrax vaccine licensed to USAMRIID is a killed vaccine tested to be free of mycoplasma incognitus (although the Army admits that "It is a difficult organism to detect under some circumstances") and has been available since the early 70s. So what makes you think it's potentially contaminated?

LH: That's the exact period of time I've been talking about. It doesn't matter of it's dead or alive. The anthrax bacterial protein, when it combines with your own host cell proteins, forms what is called an "antigenic complex": a combination of your own host cell protein with a foreign bacterial protein. The body recognizes the entire complex as foreign, and it mounts an immune response against the entire complex, including against your own host cell protein. And now you have an autoimmune illness developing that results in autoimmune diseases such as lupus, chronic fatigue, multiple sclerosis, and rheumatoid arthritis and doctors say "We don't know what caused this." They're doing it for population reduction.

WT: Of course, unlike bioweapons, vaccines can target specific groups (except perhaps for genetically-engineered bioweapons).

LH: Exactly. For example, the most plausible vaccine that initiated AIDS was the 1976 and 1978 strain of hepatitis B given to retarded children, gay men, and blacks -- the same targets as Hitler. And now they're targeting militia groups.

------------------------------------

References:

1. Horowitz, Leonard. Emerging Viruses: AIDS & Ebola. Rockport, MA: Tetrahedron Inc.; 1997. 1-888-508-4787, Email: tetra@tetrahedron.org.

2. USA Today, Dec. 16, 1997.

3. Gulf War Syndrome: the Spreading Epidemic Cover-up. Tetrahedron Inc.; 1997. Videotape. 1-800-336-9266.

4. Franz, David R. et. al. Clinical Recognition and Management of Patients Exposed to Biological Warfare Agents, J Amer. Med. Assoc. 1997; 278:402 (Aug. 6)

5. Preston, Richard. Art Bell show, Dec. 17-18 (Wed./Thurs.), 1997. See also: Preston's The Cobra Event, New York: Random House, 1997.

6. Horowitz, Leonard Larry Harris, Biological Attack, and Psychological Warfare on America. 1997.

7. Harris, Larry W. Bacteriological Warfare: A Major Threat to North America. Virtu Publishing. 1997.

8. The Riegle Report: U.S. Chemical and Biological Warfare-Related Dual Use Exports to Iraq and their Possible Impact on the Health Consequences of the Gulf War. United States Senate, 103d Congress, 2d Session May 25, 1994

9. American Gulf War Veterans Association

10. Presidential Advisory Committee On Gulf War Veterans' Illnesses Public Hearing, Thursday, May 2, 1996, Washington, D.C Testimony by Dr. Anna Johnson-Winegar, Medical, Chemical, and Biological Defense Program, U.S. Army.

11. Jane's Defense Weekly

12. Tanox Biosystems Inc.

13. Senate Report 103-97: IS MILITARY RESEARCH HAZARDOUS TO VETERANS' HEALTH?

Permission granted to freely distribute this article for non-commercial purposes if unedited and copied in full, including the BIOWAR-L footer below. Comments, questions, and counter-arguments are solicited. - Wes Thomas <west@sonic.net>

From BIOWAR-L Biowar/Bioterrorism/Toxins Mailing List
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Gulf War Vets Home Page.

[global_fiefdom]

Keep in mind this is a layman trying to peel an onion built by Nazi experts.
I need all the help and prayers and rest I can get while reading this shit and thinking about it.
May God send some real scientists to tell us the truth before another experimental vaccine is made mandatory by our traitorous presidents.

[decemberfellow]

Keep in mind this is a layman trying to peel an onion built by Nazi experts.
I need all the help and prayers and rest I can get while reading this shit and thinking about it.
May God send some real scientists to tell us the truth before another experimental vaccine is made mandatory by our traitorous presidents.

God bless you global, thank you for this info full post,  among the many names mentioned.  whenever I see bill gates funding I know this is not good.

you probably have this but for those of you that don't ...http://www.naturalnews.com/029911_vaccines_Bill_Gates.html




                                  vaccines- KILLERS IS WHAT THEY ARE

[donnay]

Bump for later...at a quick glance it looks very informative!

[global_fiefdom]

Thanks to you both!
You never know when you are inspiring someone!!!!!

[global_fiefdom]

AIDS VACCINE TO BE TESTED -2001 2003
_______________________________________________________



http://community.seattletimes.nwsource.com/archive/?date=20010518&slug=vaccine18

Friday, May 18, 2001 - Page updated at 12:00 AM


Corrected version
AIDS vaccine tests expected

By Warren King



Scientists are now optimistic there will be widespread human tests of a new generation of AIDS vaccine. The tests would be coordinated by the Fred Hutchinson Cancer Research Center in Seattle and include about 7,000 people in the United States.

"I think it's likely to happen," said Dr. Larry Corey, a Hutchinson researcher and principal investigator in the tests, which would involve 12,000 people at risk for the disease, including about 500 in Seattle. About 5,000 of the test subjects would be recruited in the Caribbean and South America. A human trial assessing the safety of the vaccine is nearing completion, and no serious side effects have been found, Corey said.

The new trial would test the vaccine's effectiveness in preventing infection by the AIDS virus, HIV. The tests could begin in early 2003, Corey said, if scientists decide the final data concerning safety warrant them.


Scientists are encouraged by the new vaccine, which deals HIV a double punch. It prods the body to increase its levels of two defenders against the virus: antibodies and "killer" cells.v

_____________________


Was the H1N1 an AIDS vaccine test?? I think it was related because if you look at the numbers, people with AIDS could have died of "secondary infection", but the truth is that uninfected healthy people died of Cytokine storm which is the opposite of what AIDS was doing.
Understand me??
_____________________________________________
PLEASE READ what this naturopath says:

http://www.hormonalfitness.com/askrob/Flu-Report-2-Cytokine-Theory-%28print%29.pdf

The Cytokine Storm
Theory of Flu Fatality:
Does it Affect Nutritional
Recommendations?
by Rob Faigin
author Natural Hormonal Enhancement,
Hormonally Intelligent Exercise
11/28/05 Boca Raton, FL

Since H5N1 has not arrived, there’s still
time to develop ideas about how to deal with
it, in the event it does arrive. I am limiting
nutritional recommendations detailed in Flu
Report 1 – “Facts about the Flu, How to
Prepare for it, and How to Fight it” to
conventional flu. I am reserving nutritional
recommendations as to H5N1, as more
information is obtained from the limited
human cases that have been identified to
date.
A central question is in what ways is H5N1
or “super flu” different from ordinary flu.
The similarities are more apparent,
especially as we move down the ladder from
H5N1 to less virulent bird flu strains, which
many commentators optimistically forecast
are more likely than H5N1 to come our way.
We may not know what we’re dealing with
until such time as it gets here, and even then
we may not know for sure whether we’re
contending with a super flu or simply a new
conventional flu strain to which we have no
preexisting immunity. As we’ll discuss in a
moment, the distinction between “super”
and “conventional” may make a difference
nutrition-wise.

One difference discussed in Flu Report 1 is
that whereas millions of people are exempt,
by way of prior exposure and acquired
immunity, from a given human flu strain,
bird flu is unrecognizable to virtually all
human immune systems when initially crossing the species barrier. This fact alone,
at such time as it becomes readily
communicable among humans, can generate
much higher flu infection rates and with it
more secondary infections and deaths. It is
believed that all forms of human influenza
originated in animals, and human flu was
first identified when animals were
domesticated and people began establishing
permanent settlements. The question of
greatest potential consequence is to what
extent H5N1 or a similar super flu is
qualitatively different from ordinary flu,
because this could mean that remedies
helpful against one may be
counterproductive against the other.

About the flu generally and cold viruses we
know this: a strong, efficient immune
system works to the advantage of resolving
infection. Conversely, with nearly every
form of infectious disease, and flu in
particular, an immune-compromised state is
associated with greater severity of infection
and higher death rates. Epidemiological
evidence from the bird flu pandemic of 1918
suggests that young adults were
disproportionately afflicted, but were they
not also disproportionately exposed relative
to the aged who tend to live more in
isolation? The deadly 1918 flu strain arrived
as troops were returning from WW1
battlefields, and mirrored troop movements
with the military port cities of Brest, France
and Boston, Massachusetts most heavily
affected.

The Cytokine Storm Theory maintains that
H5N1 behaves differently from ordinary flu,
turning the immune system against itself, via pro-inflammation proteins called “cytokines.”
Cytokines are produced by the body as a
result of certain types of stress. Cytokines
can generally be thought of as markers of
temporary biochemical disequilibrium
caused, for example, by infection or the
stress of intense exercise. They are
associated with tissue microtrauma, and are
involved in the positive adaptations induced
by exercise. One thing we know about avian
flu is that it causes extensive respiratory
tissue damage, more and deeper than
conventional flu, and this may explain why a
cytokine storm is observed. Another view is
that the tissue damage is caused by
cytokines and cytokines are overstimulated
by H5N1.

______________________________________________

AIDS victims unable to manufacture cytokine storm and die like "healthy" counterparts?

http://blogs.poz.com/paul/archives/2009/04/the_coming_cytokine.html

the coming (cytokine) storm
By Paul Dalton on April 27, 2009 3:04 PM | 5 Comments

The Swine Flu is story number one on most people's minds. Here are some titdbits.

    The terms 'swine flu' and 'bird flu' and 'avian flu' have always puzzled me. All influenza viruses circulate through both pigs and birds- some making there way to humans.\


    Read a story that some are calling for this outbreak to be renamed, 'Mexican Flu' out of respect for Muslim and Jewish sensibilities around pork. I am tempted to rant about this, but will leave it at: good luck with that.


    One of the scary aspects of this story is that young, healthy people are dying from the flu. The flu kills many people, every year- but they are most often very young (under 3 years old) or very old, often the elderly who are confined to bed.  The large pandemic flu outbreaks- 1918, 1957 and 1968- all killed a high proportion of young and otherwise healthy people.

The theory here is that these influenza strains trigger a 'cytokine storm'- an overly aggressive immune system response- which overwhelms tissues, particularly in the lungs.   This was also hypothesized as part of the SARS outbreak.

While it is typically thought that people with HIV are at higher risk of catching the flu, and of experiencing sever symptoms, could it be that in these cases the opposite could turn out to be true?

During the SARS outbreak, I read somewhere that in China, SARS ran rampant throughout this one hospital- but left the AIDS ward virtually untouched. Could it have been that the people in that AIDS ward had immune systems that were too weak to cook up a cytokine storm? Thing that make you go, hmmm?

______________________________________________

http://www.umoja-research.com/bio-attack_doc.htm

THIS IS A BIO-ATTACK ALERT, MARCH 28, 1986

 

This results from an attempt by myself and my brother to form an Health Maintenance Organization. I had difficulty estimating the probable cost of the "Human Retroviruses" as related to premium costs and was led deeper and deeper into the literature of virology attempting to solve the problem.

At first I considered testing and allowing individuals infected with the AIDS virus to form a special group, associate, insure, and have sexual relations. The literature reveals that plan will not work because the greater number of times one is infected with "Human Retroviruses" the more quickly one dies. There is a critical mass of infection which leads to reinfection of associating individuals and accelerated death. (l), I abandoned that plan.

When I considered the possibility of testing and allowing uninfected individuals to form a special group, associate, insure, and have sexual relations, I stumbled into a written order for the AIDS virus and a written plan to inject disease during preventive vaccinations for experimental purposes. I then realized the importance of the critical mass of infection. Once sufficient numbers of Americans are infected,because AIDS is not only a sexually transmissible disease, (1,2) even without sexual intercourse, the infected will reinfect each other, and the uninfected will become infected leading to an explosion of infection and disease.

Apparently, individuals in the United States National Institute of Health and National Cancer Institute have combined with the United Nation's World Health Organization to attack the United States with Bio-Weapons. (6-8):

The explosion of induced disease now rumbles through Africa.(5) The intentional introduction of disease began in Africa where sibships were inoculated by the World Health Organization's International Agency for Research on Cancer (IARC) ( with diseases obtained from the United States National Institute of Health's New Bolton Center (NBC) cell lines or diseases previously inoculated were mixed by IARC's unsterile procedures. (5 6- 8 ,l7,27,3 2,33,,35 letters and replies enclosed) other diseases were probably inoculated from other available cell cultures at other locations. In American homosexuals the virus may have been engineered to reproduce faster and for
specific attack. (3,9,39)

As usual, this warning arrives after the attack is underway. I hope that I am wrong. If I am correct, I send this warning 16 years late.

Review of recent history and science publications leads me to the conclusion that I am correct- Therefore, I send this warning to the President of the United States, the Vice-President of the United States, Governors of the several states and various federal government agencies including the Departments of State, Defense, Agriculture, NSA, FBI and CIA, and three selected members of the United States.

Page 1

UMOJA-Research.com, UMOJA Research, PO BOX 86131, Los Angeles, CA 90031