Someone mentioned finding out about the people Amy Bishop allegedly killed, here is the first one:
UAH has identified three of dead victims:
G. K. Podila, the chairman of the Department of Biological Sciences, and two associates, Maria Ragland Davis and Adriel Johnson.
Dr. G. K. Podila
Department of Biological Sciences
Engineering tree Biomass for Bioenergy. Functional Genomics of Plant-microbe interactions, Plant Molecular biology and Biotechnology
(1) Functional genomics of plant-microbe interactions: Under beneficial interactions, our lab is studying early gene expression resulting from ectomycorrhizal formation, in order to identify genes essential for ectomycorrhizal symbiosis. Our lab is one of the first labs to genetically engineer mycorrhizal fungi for functional genomic studies. Most recently, our lab is involved in coordinating the first genome-sequencing project on ectomycorrhizal fungus Laccaria bicolor by Department of Energy Joint Genome Institute. The L. bicolor genome sequence is now publicly available at JGI web site. Dr. Podila's lab is a member of International Steering committee involved in genome projects of Arbuscular mycorrhizal fungus Glomus intraradices and also poplar rust fungus Melampsora. Funding:NSF
(2) Plant Molecular Biology and Biotechnology: Our lab is pursuing molecular basis of developmental control of reproductive tissues and vascular tissues (wood formation) using poplar as a model system. Studies include cloning, characterization, and protein-protein interaction of MADS-box family transcription factors that control these processes. We are also pursuing characterization of promoters from these genes that can be used for targeted gene expression in transgenic trees and to regulate woody biomass and reproductive development. For the last 12 years our lab is involved in developing genetically engineered conifers and hardwood trees, through gene stacking techniques for increasing cellulosic biomass for bioenergy. Other ongoing projects in our lab include cloning and characterization of plant defense genes and antioxidant genes from aspen and developing transgenic trees with enhanced Resistance to pests and oxidative stresses and increased carbon sequestration. Current Funding:DOE.
(3) Bioinformatics and Functional Genomics: Our lab is currently collaborating with INRA France, CNRS, Italy, DOE Oak Ridge National labs and Michigan Tech University in developing EST databases andÂ microarray analysis for symbiotic, plant pathogenic and plant stress related differentially expressed genes and to apply these studies for Systems Biology approach to understand functioning at organismal level.
Jain P, Wadhwa P, Aygun R, Podila G.K. 2008. Vector-G: Multi-Modular SVM-Based Heterotrimeric G-Protein Prediction. In silico Biology 8, 0013.
Martin F. et. al. (2008). The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis. Nature 452(7183):88-92.
Pandey, A., White, H., Podila G.K. 2007. Functional Genomic Approaches for Mycorrhizal Research. In Plant Surface Microbiology, Springer-Verlag, Germany.
Cseke, L.J., Ravinder, N., Pandey, A.K., and Podila, G.K. 2007. Identification of PTM5 protein interaction partners, a MADS-box gene involved in aspen tree vegetative development. GENE 391: 209-222.
Hiremath ST, Balasubramanian S, Zheng J, Podila G K. 2006. Symbiosis-regulated expression of an acetylCoA acetyltransferase gene in the ectomycorrhizal fungus Laccaria bicolor. Canadian Journal of Botany 84: 1405-1416.
Gupta, P., Duplessis, S., White, H., Martin, F., Karnosky, D.F., Podila, G. K. 2005. Gene expression patterns of trembling aspen trees following long-term exposure to elevated CO2 and tropospheric O3. New Phytologist 167(1): 129-142.
Cseke LJ, Cseke SB, Ravinder N, Taylor LC, Shankar A, Sen B, Thakur R, Karnosky DF, G. K. Podila. 2005. Sep-Class Genes in Populus Tremuloides and Their Likely Role in Reproductive Survival of Poplar Trees. GENE 358: 1-16.
P. Lammers, G. A. Tuskan, S. P. DiFazio. G. K. Podila , F. Martin. 2004. Mycorrhizal symbionts of Populus to be sequenced by the United States Department of Energy's Joint Genome Institute. Mycorrhiza 14:63 n 64.
G.K. Podila, L. Lanfranco. 2004. Genomics approaches to unravel mycorrhizal symbiosis. In Plant Surface Microbiology, Springer-Verlag, Germany. Pp 561-592.
S. Sundaram, Brand, J.H, Hymes, M.J, S.T. Hiremath, G.K. Podila. 2004. Isolation and Analysis of A Symbiosis-Regulated and Ras Interacting Vesicular Assembly Protein Gene from the Ectomycorrhizal Fungus Laccaria bicolor. New Phytologist 161:529-538.
Cseke, L.J., Zheng, J., Podila, G.K. 2003. Characterization of PTM5 In Aspen: A MADS-Box Gene Expressed During Woody Vascular Development. GENE 318 (2003) 55-67.
Peter M, P-E Courty, A. Kohler, C. Delaruelle, D. Martin, D. Tagu, P. Frey-Klett, S. Duplessis, M. Chalot, G.K. Podila, F. Martin. 2003. Analysis of expressed sequence tags from the ectomycorrhizal basidiomycetes Laccaria bicolor and Pisolithus microcarpus. New Phytologist 159: 117-129.
Prior to G.K. Podila going to the University of Alabama he was at the University of Michigan.http://www.bio.mtu.edu/faculty/podila.htm
Department Faculty -
Plant Biochemistry and Molecular Biology
Dr. Gopi K. Podila Ph.D.
Adjunct Professor School of Forestry
Indiana State University, 1986
Research Area: Molecular Biology of Plant-Microbe Interactions, Forest Biotechnology
Ph: (906) 487-3068
Dr. Podila's research group specializes in the cloning and characterization of genes with the intended purpose of growing plants faster, producing more disease resistant plants and producing plant products in large quantities that are of high value. By accomplishing this, plants can be created that are more insect/disease resistant, plants that exist in extreme environments, such as hazardous waste sites, and plants that can be used for purposes of bioremediation.
1. Molecular basis for plant-microbe interactions: both beneficial and pathogenic. Under beneficial interactions, our lab is studying early gene expression resulting from ectomycorrhizal formation, in order to clone and characterize genes essential for development of mycorrhizae. Our lab pioneered the techniques to study molecular basis of early gene expression of ectomycorrhizal symbiosis. Our lab is one of the first labs to genetically engineer mycorrhizal fungi, which may be used for improving health and growth of forest trees and as biological control agents.
Under pathogenic interactions, our lab recently initiated a project on cloning pathogenecity genes from forest tree pathogens such as Septoria species to understand disease development and devise biological control methods through "gene knockout" mechanisms and also to clone R-genes from aspen against Septoria and other pathogens.
2. Plant Molecular Biology and Biotechnology: Our lab is working on developing genetically engineered conifers, such as larch; and hardwood trees, such as aspen, hybrid aspen and poplars, for value added genes such as herbicide and insect resistance and lignin modification in collaboration with School of Forestry. Other ongoing projects in our lab include cloning and characterization of plant defense genes and antioxidant genes from hardwood trees and developing transgenic trees with enhanced Resistance to pests and oxidative stresses. We are also pursuing cloning and characterization of developmentally regulated genes and promoters from hardwood species that can be used for targeted gene expression in transgenic trees and to regulate development. Currently these include genes involved in development of reproductive tissues and vascular tissues from tree species.
3. Bioinformatics and Functional Genomics: Our lab is currently collaborating with MTU faculty in Physics, Chemistry and Computer Science and Center for Biological Computing at University of Minnesota in using cutting edge computer analysis in determining the 3-D structure function relationships of proteins and also in developing EST databases and microarray analysis (in collaboration with Corning Life Sciences, Dow-Agro) for symbiotic, plant pathogenic and plant stress related differentially expressed genes.
* B.A. Wustman, E. Oksanen, J.G. Isebrands, K.S. Pregitzer, G.R. Hendrey, J. Sober, and D. F. Karnosky. G.K. Podila, 2001. Effects of Elevated CO2 and O3 on Aspen Clones Varying in O3 Sensitivity: Can CO2 Ameliorate the Harmful Effects of O3? Env. Pollution (in press).
* S. Sundaram, S.J. Kim, H. Suzuki, C.J. Mcquattie, S.T. Hiremath, G.K. Podila. (2001) Isolation and Characterization of a Symbiosis-Regulated ras from the Ectomycorrhizal Fungus Laccaria bicolor. Mol. Plant Microbe. Int. 14: 618-628.
* Liu, J.J., Karnosky, D.F., Podila, G.K. 2001. A Nonspecific Lipid Transfer Protein Gene preferentially Expressed in Developing Strobili of Pinus resinosa. Physiology and Molecular Biology of Plants 7:39-45.
* Noormets A, Sôber A, Pell EJ, Dickson RE, Podila GK, Sôber J, Isebrands JG, Karnosky DF. 2001. Stomatal and non-stomatal limitation to photosynthesis in two trembling aspen (Populus tremuloides Michx.) clones exposed to elevated CO2 and/or O3. Plant Cell Environment 24:327-336.
* Noormets, A., Karnosky, D.F., Podila, G.K. 2000. Differential induction of antioxidant enzymes in two Populus tremuloides Michx. Clones under O3-induced oxidative stress.Forest Genetics 7(4): 339-342.
* Liu, J-J. Podila, G.K. 2000. Isolation of a cDNA encoding for a putative ubiquitin-conjugating enzyme PrUBC1 from Pinus resinosa. (Accession No AF001948). (PGR 00-036) Pl. Physiol. 122:1457.
* Karnosky, D.F., B. Mankovska, K. Percy, R.E. Dickson, G.K. Podila, G. Hendrey, M.D. Coleman, M. Kubiske, K.S. Pregitzer, J. Sober and J.G. Isebrands. (1999). Effects of tropospheric O3 and interaction with CO2: Comparison of open-top chamber, field and FACE results with trembling aspen genotypes differing in O3 sensitivity. J. Air, Water and Soil Pollut. 116:311-322.
* Akkapeddi, A., Noormets, A., Deo, B.K., Karnosky, D.F., Podila, G.K. (1999). Gene structure and expression of aspen cytosolic copper/Zn-superoxide dismutase (PtSodCc1). Plant Science 143: 151-162.
* S.J. Kim, D. Bernreuther, M. Thumm, Podila, G.K. (1999). LB-AUT7, a novel symbiosis-regulated gene from an ectomycorrhizal fungus, Laccaria bicolor, is functionally related to vesicular transport and autophagocytosis.
Journal of Bacteriology 181: 1963-1967.
* Bills, S.N., Hiremath, S.T., Podila, G.K. (1999). Genetic engineering of an ectomycorrhizal fungus Laccaria bicolor for use as a biological control agent.
Mycologia 91: 237-242.
* Becker, D.M., Bagley, S., Podila, G.K. 1999. Effects of mycorrhizoplane streptomyces on gene expression and growth of ectomycorrhizal fungi and determination of the range of inhibition by the streptomyces.
Mycologia. 91: 33-40.
* S.J. Kim. Hiremath, S.T., Podila, G.K. (1999). Cloning and identification of symbiosis-regulated genes from ectomycorrhizal fungus Laccaria bicolor. Mycological Research 103: 168-172.
* S.J. Kim. Zheng, J., Hiremath, S.T., Podila, G.K. (1998). Cloning and characterization of a symbiosis- related gene from an ectomycorrhizal fungus Laccaria bicolor. Gene 222 (2): 203-212.
* Tsai, C.J., Mielke, M., Popko, J., Chiang, V.L., Podila, G.K. 1998. Red-wood in transgenic aspen expressing a homologous bi-OMT gene: Evidence for production of cinnamyl aldehydes and down regulation of CAOMT and CAD. Plant Physiology 117: 101-112.
* Karnosky, D.F., Podila, G.K. , Gagnon, Z., Pechter, P., Akkapeddi, A., Coleman, M., Dickson, R.E., Isebrands, J.G. 1998. Genetic control of responses to interacting O3 and CO2 in Populus tremuloides. Chemosphere 36: 807-812.
* Liu, J-J., Podila, G.K. 1997. Characterization of a MADS box gene from immature female cone of red pine. Plant Physiology. 113: 66.
* Sheng. Y,P., Karnosky, D.F. and Podila, G.K. 1997. Differences in O3-induced superoxide dismutase and glutathione antioxidant expression in O3 tolerant and sensitive trembling aspen (Populus tremuloides Michx.) clones.. Forest Genetics 4: 25-33.
* Tsai, C.J., Mielke, M.R., Chiang, V.L. Podila, G.K. 1996. An improved primer extension method to define transcription start points and for transgene analysis. Nucleic Acids Research. 24: 5060-5062.
* Podila, G.K. 1996. Fiber Farms for the Future: Genetically Engineered Trees. Invited review article, Chemistry & Industry 24: 764-781.
* Bills, S.N., Richter, D., Podila, G.K. 1995 Genetic transformation of symbiotic ectomycorrhizal fungus Paxillus involutus by particle bombardment. Mycological Research 99: 557-561.
* Tsai, C.J., Podila, G.K., Chiang, V.L. 1995. Nucleotide sequence of Populus tremuloides gene for caffeic acid/5 hydroxyferulic acid O-methyltransferase. Pl. Physiol. 107: 1459.
* Podila, G.K., San Francisco, M.J., Rosen, E., Kolattukudy, P.E. 1995. Targeted secretion of cutinase in Fusarium solani f.sp. pisi and Colletotrichum gloeosporioides. Phytopathology 85: 238-242.
* Tsai, C.J., Podila, G.K., Chiang, V.L. 1995. Agrobacterium-mediated transformation of quaking aspen (Populus tremuloides) and regeneration of transgenic plants. Pl. Cell Reports 14: 94-97.
* Shin, D., Podila, G.K., and Karnsoky, D.F. 1994. Transformation and regeneration of larch for herbicide and insect resistance.
Can. J. For. Res. 24: 2059-2067.
* Akkapeddi, A.S., Stanek, M.T., Shin, D., Karnosky, D.F., Podila, G.K. 1994. cDNA and derived amino acid sequence of the chloroplastic copper/zinc superoxide dismutase from aspen. Pl. Physiol. 106: 1231-1232.
* Dwivedi, U.N., Campbell, W.H., Yu, J., Datla, R.S.S., Chiang, V.L., Podila, G.K. 1994. Modification of lignin biosynthesis in transgenic Nicotiana through expression of an antisense O-methyltransferase gene from Populus. Plant Molecular Biology 26: 61-71
* Podila, G.K., Rogers, L.M., Kolattukudy, P.E. 1993. Chemical signals from avocado surface wax trigger germination and appressorium formation in Colletotrichum gloeosporioides. Plant Physiology 103: 265-272.
* Podila, G.K., Kotagiri, S., and Shantharam S. 1993. Molecular cloning of protocatechuate 3,4-dioxygenase genes from Bradyrhizobium japonicum USDA110. Appl. Env. Microbiol 59: 2717-2719
* Varley, D., Hiremath, S.T. and Podila, G.K. 1992. Cutinase gene expression in Cryphonectria parasitica, the chest nut blight fungus: Effect of hypovirulence agents on expression. Mol. Cell. Biol. 12: 4539-4544.
* Bajar, A.M., G.K. Podila, and P.E. Kolattukudy. 1991. Identification of fungal cutinase promoter that is inducible by plant signal via a phosphorylating transacting factor.
Proceedings of National Academy of Science. USA. 88: 8208-8212.
* Dickman, M.B., G.K. Podila, and P.E. Kolattukudy. 1989. Insertion of cutinase gene into a wound pathogen enables it to infect intact host.
* Podila, G.K., M.B. Dickman, and P.E. Kolattukudy. 1988. Transcriptional activation of a cutinase gene in isolated fungal nuclei by plant monomers. Science 242:922-925.
Book Chapters and Proceedings Papers:
* G.K. Podila and M. Badiani. (2001). Antioxidants and Foliar Defense Compounds. In "The Impact of Carbon Divide and Other Greenhouse Gases on Forest Ecosystems". D. Karnosky, R. Ceulemans, J. Innes and G.E. Scarascia Mugnozza, Eds, IUFRO (in press).
* Karnsoky, D.F., Sen, B., Kim, J., Xiang, B, Cseke, L, Dixon, D.C, Liu, .J, Podila, G.K. (2000). Engineering reproductive sterility in forest tree species. Proceedings of the 8th International Workshop of Bio-Refor. Biotechnology Applications for Reforestation ad Biodiversity Conservation. Bio-Refor Publications, Nepal. 7-12.
* S.T. Hiremath and G.K. Podila. (2000). Development of Genetically Engineered Mycorrhizal Fungi for Biological Control. In Current Advances in Mycorrhizae Research. G.K. Podila and D.D. Douds Eds. APS Press, St. Paul. MN. 179-187.
* Karnosky, David F., Kevin Percy, Blanka Mankovska, Richard E. Dickson, J.G. Isebrands, and G.K. Podila (2000). Genetic implications for forest trees of increasing levels of greenhouse gases and UV-B. In Forest Genetics and Sustainability, C. Matyas (ed.). Kluwer Academic Publishers. The Netherlands. Vol 63: 111-124.
* Bauman, A., Brown, R., Dettman, R., Mellen, A., Pandey, R., Podila, G.K., Xiang, X.-H., and Murthy,P. (1998) Conformational studies of myo-inositol phosphates. In Proceedings of Workshop on the Biochemistry of Plant Phytate and Phytic acid. S. Rasmussen, Ed., Kluwer Academic Publishers, Copenhagen, Denmark.
* Karnosky, D.F., Podila, G.K. Chiang, V.L. and Reimenschneider, D. (1997). "Biotechnology in Forest Tree Improvement”. In: Forest Genetics and Tree Breeding (Eds. A.K. Mandal, G.L. Gibson), CBS Publishers & Distributors, New Delhi, India 15:252-268.
* Karnosky, D.F., Podila, G.K. and Reimenschneider, D. 1997. Differential expression of aroA gene in transgenic hybrid poplar: Influence of promoter and ozone stress. In Klopfenstein, N.B. ed., Populus: A model system for tissue culture and molecular biology of woody plants. USDA Forest Service Technical Report RM-GTR-297. Pp. 70-73.
* Boerjan, W., Baucher, M., Chablet, B., Petit-Conil, M., Leple, J.C., Cornu, D., Monties, B., Van Montagu, M., Van Doorsselaere, J., Inze, D., Jousnin, L., Tsai, C.J., Podila, G.K., Joshi, C.P., Chiang, V.L. (1997). Genetic modification of lignin biosynthesis in quaking aspen (Populus tremuloides) and poplar (Populus tremula x Populus alba). In: Klopfenstein, N.B. ed., Populus: A model system for tissue culture and molecular biology of woody plants. . USDA Forest Service Technical Report RM-GTR-297.
* Hiremath, S.T., Podila, G.K. (1995). Biocontrol of white grubs through genetically engineered ectomycorrhizae. Proceedings of 2nd International Symposium on Applied Biotechnology Bloomington, MN, October 2-6, USDA Technical Report NC-175, p68-69, St. Paul, MN.
* Karnosky, D.F., Podila, G.K., Tsai, C.J., Chiang, V.L. (1994). Progress in production of transgenic trees with value added genes: Results from larch and aspen. TAPPI Proceedings. p157-160. TAPPI Press
* Chiang, V.L., Tsai, C.J. Kumar, A.S., Podila, G.K. (1994). Regulation of lignin biosynthesis in transgenic quaking aspen (Populus tremuloides). TAPPI Proceedings. Atlanta, GA. p167-172, TAPPI Press, Atlanta, GA
* Chiang, V, L., Podila G.K., Tsai, C.J. Kumar, A.S., Yu, J. 1994. Regulation of bi-functional O-methyltransferase gene expression in transgenic quaking aspen (Populus tremuloides). Intl. Wood Biotechnology Symposium. Tokyo, Japan. P15-22.
* Karnosky, D.F., Shin, D., Podila, G.K. (1994). Transfer and expression of foreign genes in Larix: Opportunities for genetic improvement. Proc. International Larix Symposium. USDA Forest Service GTR-INT-319. Pp. 405-407.
* Shin, D.I., Podila, G.K., and Karnosky, D.F. (1994). Transformation of Larix decidua. In: Y.P.S. Bajaj (Ed.). Biotechnology in Agriculture. Springer-Verlag. Invited Chapter. Vol 29. Pp 321-336.
* Karnosky, D.F. and Podila, G.K. (1993). Elm Improvement Through Biotechnological Methods. In Dutch Elm Disease Research, ed. M.B. Sticklen, and J.L. Sherald. Springer-Verlag, New York. pp.75-80.
* Chiang, V.L., Podila, G.K., Wang, W.Y., Bugos, R.C., Campbell, W.H., Tsai, C.J. (1993). Genetic manipulation of lignification in Liquidamber styraciflua. Proceedings of International conference on Emerging Technologies for Pulp and Paper Industry, Taipei, Taiwan, May 18-20, pp. 26-29.
* Dwivedi, U.N., Campbell, W.H., Yu, J, Datla, R.S.S., Bugos, R.C., Chen, Z.Z., Wang, W.Y., Podila, G.K., and Chiang, V.L. (1993). Expression of lignin specific aspen O-methyltransferase antisense gene in tobacco and wood species to reduce lignin content. Proceedings of 7th International Symposium on Wood and Pulping Chemistry, Beijing, China, May 25-28, pp. 155-158.
* Kolattukudy, P.E., G.K. Podila, B.A. Sherf, and R. Mohan. (1991). Mutual triggering of gene expression in plant-fungus interactions. Molecular Genetics of Plant-Microbe Interactions. Vol. 1, 242-249.
* Podila, G.K., M.B. Dickman, L. Rogers, and P.E. Kolattukudy. (1989). Regulation and expression of fungal genes by plant signals. Pages 217-226 In: Nevelainen, H., and M. Penttila, Eds. Molecular Biology of Filamentous Fungi. Foundation for Biotechnical and Industrial Fermentation Research. Invited Chapter.
* Kolattukudy, P.E., Podila, G.K., Roberts, E., and Dickman, M.B. (1989). Gene expression resulting from the early signals in plant-fungus interaction. In UCLA symposium Proceedings on Molecular Biology of Plant-Pathogen Interactions. p 87-104.
* Current Advances in Mycorrhizae Research, (2000) Editors G.K. Podila and D.D. Douds, American Phytopathological Society Press, and St. Paul, MN.